pyXenium.mechanostress.compute_ane_density

compute_ane_density(axes, *, radii_um=DEFAULT_MECHANOSTRESS_RADII_UM, angle_col='axis_angle_radians', x_col='centroid_x', y_col='centroid_y', groupby=None, return_cell_metrics=False)

Compute Aligned Neighbour Energy density across radius-based neighborhoods.

Parameters:

• axes (DataFrame)

• radii_um (Sequence[float])

• angle_col (str)

• x_col (str)

• y_col (str)

• groupby (str | Sequence[str] | None)

• return_cell_metrics (bool)

Return type:

DataFrame | tuple[DataFrame, DataFrame]